static void Main(string[] args)
{
    int[,] matrix = new int[2, 2];
    FillMatrix(matrix);
    // matrix is now full of -1
}

public static void FillMatrix(int[,] matrix)
{
    for (int i = 0; i < matrix.GetLength(0); i++)
    {
        for (int j = 0; j < matrix.GetLength(1); j++)
        {
            matrix[i, j] = -1;
        }
    }
}